Changing lifestyle shouldn't require heroic willpower.
- Prof. Lucas Spierer
- Jul 6
- 6 min read
There are scientific findings that seem to confirm an old intuition, one we may have come to underestimate: sustained support for health behaviors can change the trajectory of a life.
A study published in JAMA drives this home forcefully. Adults with prediabetes, originally enrolled in the Diabetes Prevention Program, were followed for up to 21 years. Three groups were compared: an intensive lifestyle intervention, metformin treatment, or a placebo. The goal was no longer just to look at the onset of diabetes, but something broader: multimorbidity, meaning the accumulation of multiple chronic diseases over time.
The result is worth pausing on. In this population, the lifestyle intervention was associated with a lower risk of multimorbidity than placebo. Metformin, on the other hand, showed no significant benefit on this specific outcome.
This isn't a conclusion against medication. That would be too quick a reading, and probably a wrong one. But it is an important reminder: health behaviors aren't a decorative add-on to care. They can carry real weight, even over very long time horizons.
The lifestyle intervention studied wasn't just advice given at the end of a consultation, either. It was based on a structured program: reducing caloric and fat intake, at least 150 minutes of physical activity per week, and a weight loss target of at least 7%. It's precisely this intensity of support that makes the study interesting. It shows that when people are genuinely supported through their changes, the effect isn't limited to a short-term marker. It can shape the overall trajectory of their health.
Salive ME, Tjaden AH, Ames JR, et al. Lifestyle and Metformin Interventions and Risk of Multimorbidity in Adults With Prediabetes. JAMA. Published online June 15, 2026. doi:10.1001/jama.2026.8492
But this study also raises another, more uncomfortable question: if lifestyle changes matter this much, why are they so hard to sustain?
"Lifestyle," a simple word for a complicated reality
In public discourse, "changing your lifestyle" often sounds obvious. Move more. Eat better. Cut back on sugary products. Sleep more. Drink less. Quit smoking.
On paper, almost no one disputes these recommendations. The problem starts when they meet real life.
Real life is a commute that's too long, a day that's too packed, a sick child, accumulating stress, a fatigue that makes everything harder. It's also an environment where the most appealing foods are available everywhere, all the time, often cheaper, more visible, faster. Individual "choice" exists, of course. But it rarely happens in a calm laboratory, after a good night's sleep, with intact motivation.
Asking someone to durably change their lifestyle isn't just asking them to understand what's good for their health. Most patients already know that. It's asking them to change gestures repeated hundreds of times, within an environment that keeps pushing the other way.
This is where many approaches fail. They add information, goals, reminders, sometimes charts to fill in. They assume the person will be able to muster, every single day, the attention needed to resist, choose, anticipate, correct. But that attention is a limited resource.
By making everything rest on it, prevention sometimes turns into a moral trial.
What we often forget: wanting itself can cause suffering
In prevention programs, there's a lot of talk about weight, blood sugar, cholesterol, step counts, what's on the plate. Much less about craving.
The word is sometimes poorly translated. "Desire" sounds too light. "Urge" sounds too heavy. Craving sits somewhere between the two: a strong, insistent want that sometimes seems to precede the decision itself. A sugary drink glimpsed in a fridge. A pastry on a meeting table. The opened bag in the evening, after a long day. The person didn't necessarily "decide" to want it. The want is just there.
And it can be painful.
This particular suffering is rarely discussed. It doesn't always carry the legitimacy of physical pain or clearly named anxiety. Yet it wears people down. It creates tension, guilt, a sense of losing control. It can feel like being in permanent conflict with oneself.
This dimension is essential for a non-stigmatizing approach. Because if craving isn't seen, the behavior risks being misread. People say: "lack of willpower," "lack of discipline," "poor motivation" — when part of the problem actually plays out earlier, in automatic patterns.
Bewe's scientific materials describe craving as a response tied to the activation of reward circuits in reaction to certain environmental cues. When a problematic cue is perceived — for example, a highly valued food or drink — it can trigger a motivational response that then favors consumption.
Put more simply: the urge doesn't always arrive after reflection. It often arrives before it.
Less conscious effort, more work on automatic patterns
This is where the approach needs to change.
Information obviously still matters. Therapeutic patient education keeps a central role: understanding one's condition, identifying risk factors, recognizing one's resources, building realistic strategies. But therapeutic education isn't a lecture. It's not a more polite way of telling patients what they should do.
It's support. A way of restoring a sense of agency, without denying real constraints.
But for certain consumption behaviors, part of the work has to target what escapes conscious decision-making: habits, cues, automatic responses, the value the brain assigns to certain foods or drinks.
Bewe fits into this logic. The idea isn't to ask the user to think more about their cravings, count more, monitor more, or "control themselves" harder. The goal, instead, is to reduce friction by acting on the automatic roots of the behavior.
Concretely, the solution relies on neurocognitive tasks built into games. The user plays. Meanwhile, repeated training pairs certain stimuli with specific motor responses, aiming to gradually shift the automatic value assigned to those stimuli. Bewe's materials describe this approach as a digital intervention that targets the reward response to problematic items, drawing on tasks such as Go/No-Go and Cue-Approach Training.
This point matters: the intervention doesn't ask the person to fight an inner debate at every single temptation. It seeks to make certain temptations less overwhelming in the first place.
It's a subtle but major difference. In many programs, the person is helped to resist better. Here, the aim is also to reduce what they have to resist.
What this changes for prevention
The JAMA study reminds us that lifestyle support can have a lasting impact. But it also reveals, implicitly, the difficulty of scaling it: how do you offer this kind of support to many people, over a long period, without exhausting patients, caregivers, and health systems?
This is probably one of the great questions of modern prevention.
We can't simply tell people, "You know what to do, so do it." Nor can we assume everyone will have continuous access to intensive support. And we can no longer ignore the automatic mechanisms that make certain behaviors so resistant to change.
If lifestyle interventions are to become genuinely sustainable, their mental cost needs to come down. Less burden. Less guilt. Less reliance on willpower. More tools that work with how the brain actually learns.
Data reported by Bewe shows, in randomized controlled trials, a reduction in targeted cravings or preferences and a decrease in consumption of the targeted items. These results don't mean a digital tool replaces medical, nutritional, or psychological support when it's needed. They suggest instead that there's a complementary lever available: helping people act before the conscious struggle even begins.
Taking craving seriously, without inducing guilt
Craving is still too often treated as a detail. A secondary discomfort. Something the person should learn to master.
That's a mistake.
For many patients, this is exactly where part of the change plays out — not in knowledge, which is often already there, but in the precise moment when the urge overtakes the intention. That moment is brief, intimate, sometimes shameful. And yet it's central.
Recognizing this changes how we support people.
We no longer ask: "Why didn't you resist?" We ask: "What makes this situation so difficult?" We no longer say: "You need more discipline." We look for: "How do we weaken the trigger?" We stop reducing the person to their behavior. We look instead at the system in which that behavior appears.
This, too, is what therapeutic education means: not confusing responsibility with guilt. A person can be an active participant in their own health without being held solely responsible for every obstacle they encounter.
Lifestyle changes are essential. The JAMA study confirms this with long-term data. But for them to become realistic, we need to stop presenting them as simply a matter of willpower.
The real question may no longer be just: how do we better treat chronic diseases once they've taken hold?
It's also: how do we help people earlier, more simply, and with less friction, to prevent these diseases from accumulating in the first place?
Taking craving seriously isn't a psychological detail. It's a fairer, more human, and probably more effective way of approaching prevention.



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